There aren’t many details about Hajime no Ippo The Fighting! DS on the teaser site. A few screenshots flash by showing the actual boxing takes place on the touch screen. From the look of this training screenshot it appears you tap targets to punch them. There is some kind of multiplayer mode too so you can see who jabs the screen the best. Japan is scheduled to get this on December 4 with D3 acting as the publisher. D3 and ESP seem to be quite friendly nowadays.
Images courtesy of D3 Publisher/ESP.