Disaster Report 4: Summer Memories (or if you prefer The Desperate City 4: Summer Memories) has two lead characters. You can choose either a male or female protagonist at the beginning of the game just like Disaster Report 3 which came out for PSP.
It isn’t clear how the game’s story and/or dialogue choices differ depending on the lead character, but given the kinds of tongue-in-cheek options Irem add for a bit of humor at least some lines have to be different.
Disaster Report 4 is slated for a winter release in Japan. The game supports PlayStation Move and 3D TVs, although Irem hasn’t said much about those features at this time.