First Hokage vs. Sarutobi and the Monkey King. The Second vs. Minato’s rasengan. You can set up those fights in Naruto Shippuden: Ultimate Ninja Storm Generations. CyberConnect2’s upcoming fighting game has all five hokages available as playable characters. Minato is unique since he’s in the game twice as the Fourth Hokage and a younger teacher from the Kakashi Gaiden arc.
The First Hokage
The Second Hokage
The Third Hokage
Minato (Kakashi Gaiden arc version)
Minato (the Fourth Hokage version)
Shizune (support character only)